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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
13.03
Human Site:
S438
Identified Species:
23.89
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
S438
S
T
V
G
Q
S
F
S
E
Q
H
I
S
Q
L
Chimpanzee
Pan troglodytes
XP_518428
831
92792
S614
S
T
V
G
Q
S
F
S
E
Q
H
I
S
Q
L
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
S614
S
T
I
D
Q
S
F
S
E
Q
H
I
S
Q
L
Dog
Lupus familis
XP_850330
823
92006
N606
P
N
A
E
Q
S
F
N
E
Q
D
I
S
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
T438
S
L
T
R
Q
D
I
T
Q
L
E
E
S
I
R
Rat
Rattus norvegicus
NP_001020897
655
73837
T438
V
E
R
S
L
T
L
T
Q
Q
D
I
T
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
N354
T
A
G
N
F
L
L
N
P
L
E
A
K
N
A
Chicken
Gallus gallus
XP_419265
754
84415
N539
S
S
E
E
Q
S
F
N
E
Q
E
I
S
H
L
Frog
Xenopus laevis
NP_001085122
605
68633
E413
R
K
E
I
S
S
E
E
Q
E
G
S
S
A
M
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
D422
S
Q
G
C
R
V
Q
D
G
E
S
L
T
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
P596
G
S
A
V
S
T
A
P
D
H
L
V
K
M
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
Y253
R
L
Q
R
D
V
C
Y
K
R
V
P
K
S
S
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
I512
S
T
F
D
I
S
N
I
S
Q
S
S
D
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
86.6
60
N.A.
20
20
N.A.
0
60
13.3
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
33.3
46.6
N.A.
13.3
73.3
33.3
33.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
0
0
0
8
0
0
0
0
8
0
16
16
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
8
0
8
8
0
16
0
8
0
0
% D
% Glu:
0
8
16
16
0
0
8
8
39
16
24
8
0
0
8
% E
% Phe:
0
0
8
0
8
0
39
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
16
16
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
24
0
0
16
0
% H
% Ile:
0
0
8
8
8
0
8
8
0
0
0
47
0
8
0
% I
% Lys:
0
8
0
0
0
0
0
0
8
0
0
0
24
0
0
% K
% Leu:
0
16
0
0
8
8
16
0
0
16
8
8
0
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
8
0
8
0
0
8
24
0
0
0
0
0
8
8
% N
% Pro:
8
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% P
% Gln:
0
8
8
0
47
0
8
0
24
54
0
0
0
31
0
% Q
% Arg:
16
0
8
16
8
0
0
0
0
8
0
0
0
0
8
% R
% Ser:
54
16
0
8
16
54
0
24
8
0
16
16
54
8
8
% S
% Thr:
8
31
8
0
0
16
0
16
0
0
0
0
16
8
0
% T
% Val:
8
0
16
8
0
16
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _